Waters Affinity Isothermal Titration Calorimeter LV What is it?
ITC (Isothermal titration calorimetry) is a method for complete characterization of the basic chemical details of a binding interaction. The method determines a binding constant, reaction stoichiometry, and total reaction energy of two or more compounds (small or large molecules) in solution. Isothermal titration calorimeters do this by measuring the heat that is released or absorbed when molecules interact with each other. Temperature conditions can be controlled to understand the temperature dependence of binding.
Manufacturer: TA Instrument
Model Name: Affinity ITC LV
Applications: Interaction study of two or more compounds in solution
Instrument Overview: The Affinity ITC allows researchers to characterize the binding of their samples without the use of exogenous tags or dyes, thereby simplifying workflows and reducing errors in biopharmaceutical development. Researchers simultaneously collect stoichiometry data during binding characterization to verify whether a 1-to-1 binding interaction occurs, eliminating the need for other tests. The affinity ITC allows researchers to test their materials under their desired conditions, without reliance on manufacturer-required reagents. Researchers simultaneously collect stoichiometry data during binding characterization and can verify whether a 1-to-1 binding interaction occurs, eliminating the need for other tests.
Technical features and specifications:
Cell Geometry: Fixed Cylindrical
Cell Composition: 24K Gold
Active Cell Volume: 190 µl
Operating Temperature Range: 2°C to 80°C
Minimum Detectable Heat: 0.04 µJ
Maximum Measurable Heat: 5000 µJ
Low Noise Level : 0.0013 µW
Baseline Stability: 0.02 µW/hr
Temperature Stability: 8 µ °C at 25 °C
Temperature Control: Active heating & cooling
Response Time: 3.3 sec
Injection Syringe Volume: up to 250 µL
Injection Volume Precision: 0.01 µL
Stirring Speed Range: 0 to 200 rpm
Injection Syringe Cleaning/Rinsing: Fully automated
Wash/Rinse Solvent Ports: 4 on back of instrument
Charges:
User operated: $500/day, Staff operated: $600/day
Instrument Manufacturer URL:https://www.tainstruments.com/affinity-itc-auto/
Detailed Specifications:
N.A.
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