A*STAR Scientific Equipment Finder

Metabolomics: Xevo TQ-XS coupled to ACQUITY Premier UPLC

equipment

What is it?
The Waters Xevo TQ-XS is an upgrade of our current Xevo TQ-S triple quadrupole LC-MS system. It is the most sensitive and the most accurate absolute quantitation of small molecules our group can offer. LC separation is performed using the ACQUITY Premier LC system. It uses the novel MaxPeak High Performance Surfaces (HPS) technology to maximise analyte detection. This technology is known to reduce analyte and metal surface interaction.

Manufacturer: Waters

Model Name: Waters Xevo TQ-XS MS and Waters ACQUITY Premier LC

Applications: Absolute quantitation of small molecules

Instrument Overview: The Waters Xevo TQ-XS LC-MS system offers the most sensitive and the most accurate targeted metabolomics workflow. The MS hardware is equipped with StepWave XS™ ion optics for the greatest level of sensitivity, selectivity and accuracy. The increased MS ion intensities while minimizing background noise will provide more confidence in assay repeatability. The MS is coupled to the latest Waters ACQUITY Premier LC for maximum sample separation.

Technical features and specifications:
Mass range: 2 to 2048 m/z
Ion source: A combined ESI/APCI source
Detector: The detector have a linear dynamic range of 6 orders of magnitude (metabolite dependent); Switching of polarity is within 0.015 seconds
Acquisition mode: Full scan MS, product ion scan, precursor ion scan, constant neutral loss scan, selected ion monitoring (SIR), multiple reaction monitoring (MRM), simultaneous multiple MRM in parallel to full scan, parent ion scan and neutral loss (in both polarity)
Software: MassLynx (instrument setup), TargetLynx (data processing and analysis)

Charges:
NA

Instrument Manufacturer URL: https://www.waters.com/waters/en_US/Xevo-TQ-XS-Triple-Quadrupole-Mass-Spectrometry/nav.htm?locale=en_US&cid=134889751

Detailed Specifications:
NA

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